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05:29 Substrate Elasticity Influences TRPV4… Substrate Elasticity Influences TRPV4 Mechanotransduction in Chondrocytes, Nicholas Trompeter	Substrate Elasticity Influences TRPV4 Mechanotransduction in Chondrocytes, Nicholas Trompeter Osteoarthritis (OA) is the most common joint disorder in the United States, affecting over 54 million adults. During OA progression, the stiffness of cartilage decreases due to degradation of the… ntromp@udel.edu biomedical engineering chondrocytes trpv4 stiffness apoptosis cells cartilage trip function gels osteoarthritis expression response gel decrease trippy factors propidium challenge influences chondrocyte metalloproteinases stimulation From Lauren Mosesso on April 15th, 2021 0 likes 5 plays 0 Department Name Biomedical Engineering
04:41 Unilateral, daily bouts of muscle loading leads… Unilateral, daily bouts of muscle loading leads to mineral and extracellular adaptation of the immature Achilles enthesis in mice, Elahe Ganji	Unilateral, daily bouts of muscle loading leads to mineral and extracellular adaptation of the immature Achilles enthesis in mice, Elahe Ganji The tendon-to-bone attachment (i.e., enthesis) translates force from tendon to bone. The enthesis matures during postnatal growth and is susceptible to overuse injuries. Increased activity during… muscle loading achilles enthesis adaptation mechanical engineering elaganji@udel.edu loading muscle channelrhodopsin bone weeks model attachment control stimulation optogenetics growth tissue response overuse bit fiber destruction vascularization mature histology From Lauren Mosesso on April 15th, 2021 0 likes 6 plays 0 Department Name Mechanical Engineering

05:29

Substrate Elasticity Influences TRPV4…

Substrate Elasticity Influences TRPV4 Mechanotransduction in Chondrocytes, Nicholas Trompeter

Osteoarthritis (OA) is the most common joint disorder in the United States, affecting over 54 million adults. During OA progression, the stiffness of cartilage decreases due to degradation of the…

From Lauren Mosesso on April 15th, 2021 0 likes 5 plays 0

Department Name

Biomedical Engineering

04:41

Unilateral, daily bouts of muscle loading leads…

Unilateral, daily bouts of muscle loading leads to mineral and extracellular adaptation of the immature Achilles enthesis in mice, Elahe Ganji

The tendon-to-bone attachment (i.e., enthesis) translates force from tendon to bone. The enthesis matures during postnatal growth and is susceptible to overuse injuries. Increased activity during…

From Lauren Mosesso on April 15th, 2021 0 likes 6 plays 0

Department Name

Mechanical Engineering